ENANTIOSELECTIVITY AND REACTIVITY OF IMMOBILIZED LIPASE IN SUPERCRITICAL CARBON-DIOXIDE

Authors
CERNIA E PALOCCI C GASPARRINI F MISITI D FAGNANO N
Citation
E. Cernia et al., ENANTIOSELECTIVITY AND REACTIVITY OF IMMOBILIZED LIPASE IN SUPERCRITICAL CARBON-DIOXIDE, Journal of molecular catalysis, 89(1-2), 1994, pp. 120000011-120000018
Citations number
6
Categorie Soggetti
Chemistry Physical
Journal title
Journal of molecular catalysis → ACNP
ISSN journal
03045102
Volume
89
Issue
1-2
Year of publication
1994
Pages
120000011 - 120000018
Database
ISI
SICI code
0304-5102(1994)89:1-2<120000011:EAROIL>2.0.ZU;2-5
Abstract
Some results and some general observations on the reactivity of differ ent substrates in lipase-catalyzed reactions in supercritical carbon d ioxide are reported. Chiral 1-phenylethanol, 2-octanol, 6-methyl-5-hep ten-2-ol and trans-3-penten-2-ol have been prepared in high enantiomer ic excess (ee > 80%) by enantioselective acetylation of the correspond ing racemic alcohols using immobilized crude lipase (Pseudomonas sp. f rom Amano) in supercritical carbon dioxide.