DETERMINATION OF HEXAMETHYLENE DIISOCYANATE IN SPRAY-PAINTING OPERATIONS USING CAPILLARY ZONE ELECTROPHORESIS

Capillary zone electrophoresis (CZE) was used for the analysis of hexa methylene diisocyanate (HDI) vapor during spray-painting operations. T he use of CZE when compared with high-performance liquid chromatograph y (HPLC) offers improved resolution of coeluting peaks, comparable lim its of detection and speed of analysis, low solvent consumption, and t he ability to sample as little as 3 mu L of sample. The modified OSHA method 42, which uses capillary zone electrophoresis for the analytica l determination of HDI, was validated in a direct comparison with the original OSHA method 42. Field samples were obtained during several sp ray-painting operations. The results obtained using CZE were comparabl e (r = 0.998) to those obtained using HPLC.