Mixing produced by Rayleigh-Taylor instability at the interface betwee
n two layers is the subject of a comparative study between laboratory
and numerical experiments. The laboratory experiments consist of a lay
er of brine initially at rest on top of a layer of fresh water. When a
horizontal barrier separating the two layers is removed, the ensuing
motion and the mixing that is produced is studied by a number of diagn
ostic techniques. This configuration is modelled numerically using a t
hree-dimensional code, which solves the Euler equations on a 180(3) gr
id. A comparison of the numerical results and the experimental results
is carried out with the aim of making a careful assessment of the abi
lity of the code to reproduce the experiments. In particular, it is fo
und that the motions are quite sensitive to the presence of large scal
es produced when the barrier is removed, but the amount and form of th
e mixing is not very sensitive to the initial conditions. The implicat
ions of this comparison for improvements in the experimental and numer
ical techniques are discussed.