Pressure measurements in orthopaedics are hampered by the fact that th
e required measuring range is a factor of 20 higher than the common ph
ysiological range. A sensor system has been designed, based on a previ
ously reported microsensor placed in a closed-loop configuration, in w
hich the pressure across the microsensor membrane is kept constant. Th
e backside of this membrane is connected to a pneumatic unit, with a h
igh-pressure source and an electromagnetic valve, controlled by the ou
tput signal from the microsensor. The prototype system has excellent l
inearity, and a dynamic range of 67 dB, a 24 dB improvement compared w
ith the open-loop system. Rise and fall times are 0.6 and 0.2 s, respe
ctively, limited by the compliance and flow resistance of the pneumati
c system. Recordings of intradiscal pressure have been made on animal
carcasses, and on patients suffering from lumbar back pain. Intradisca
l pressure measurements could, potentially, be valuable in the diagnos
is and understanding of the pathogenesis of this disease.