PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY IN AN HIV-INFECTED CHILD

A child with perinatally acquired HIV infection presented with acute n eurologic deterioration. A cerebellar white matter lesion seen on CT a nd MRI later proved to be progressive multifocal leukoencephalopathy ( PML) by histology. Although a recognized disease of HIV-infected adult s, PML is certain to be seen with more frequency in HIV-infected child ren who are surviving longer as a result of improved medical care. Rec ognition of the clinical and radiographic manifestations is important because of the dismal prognosis.