TERTIARY STRUCTURAL CATEGORIES OF LEIUROTOXIN AND SOME OTHER SCORPION-VENOM TOXINS

Authors
NARAYANAN P
Citation
P. Narayanan, TERTIARY STRUCTURAL CATEGORIES OF LEIUROTOXIN AND SOME OTHER SCORPION-VENOM TOXINS, Current Science, 66(9), 1994, pp. 680-682
Citations number
12
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Current Science → ACNP
ISSN journal
00113891
Volume
66
Issue
9
Year of publication
1994
Pages
680 - 682
Database
ISI
SICI code
0011-3891(1994)66:9<680:TSCOLA>2.0.ZU;2-Q
Abstract
Similarly-placed cysteine residues (and in-register disulphide bridges ) in CnII-11 (C. noxius), noxius-toxin, charybdotoxin and leiurotoxin I, and amino acid sequence homology among these scorpion venom toxins enable classification of these molecules under CnII-11 type tertiary s tructural category under scorpion-toxin type proteins. Similar structu ral motif is also found in bee venom toxin apamin and apamin-type pept ides. Neurotoxin P2 (Amm P2) should be classified under the I5A type t ertiary structure.