We give a new formulation to the multiple-depot vehicle scheduling pro
blem as a set partitioning problem with side constraints, whose contin
uous relaxation is amenable to be solved by column generation. We show
that the continuous relaxation of the set partitioning formulation pr
ovides a much tighter lower bound than the additive bound procedure pr
eviously applied to this problem. We also establish that the additive
bound technique cannot provide tighter bounds than those obtained by L
agrangian decomposition, in the framework in which it has been used so
far. Computational results that illustrate the robustness of the comb
ined set partitioning-column generation approach are reported for prob
lems four to five times larger than the largest problems that have bee
n exactly solved in the literature. Finally, we show that the gap asso
ciated with the additive bound based on the assignment and shortest pa
th relaxations can be arbitrarily bad in the general case, and as bad
as 50% in the symmetric case.