A TANDEM CLAISEN-DECARBOXYLATION-ALDOL REACTION THE FREDERICAMYCIN-A CORE

Authors
BASKARAN S NAGY E BRAUN M
Citation
S. Baskaran et al., A TANDEM CLAISEN-DECARBOXYLATION-ALDOL REACTION THE FREDERICAMYCIN-A CORE, Liebigs Annalen, (2), 1997, pp. 311-312
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
2
Year of publication
1997
Pages
311 - 312
Database
ISI
SICI code
0947-3440(1997):2<311:ATCRTF>2.0.ZU;2-R
Abstract
A tandem reaction of doubly deprotonated indanecarboxylic acid 3 with ethoxyphthalide 5 leads to the formation of the spirocyclic diastereom ers 6a and the 6b in a ratio of 9:1. They are converted to the spirodi ketone core 2 of fredericamycin A (1).