PHLEBIACHRYSOIC ACIDS, NEW INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS FROM PHLEBIA-CHRYSOCREA (BASIDIOMYCETES)

Authors
MARUMOTO R KLOSTERMEYER D STEGLICH W WUNDER A ANKE T
Citation
R. Marumoto et al., PHLEBIACHRYSOIC ACIDS, NEW INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS FROM PHLEBIA-CHRYSOCREA (BASIDIOMYCETES), Liebigs Annalen, (2), 1997, pp. 313-316
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Liebigs Annalen → ACNP
ISSN journal
09473440
Issue
2
Year of publication
1997
Pages
313 - 316
Database
ISI
SICI code
0947-3440(1997):2<313:PANIOL>2.0.ZU;2-X
Abstract
Five yellow 2-hydroxy-5-methoxybenzoquinones with C(15)and C-17 alkyl side chains were isolated from fruitbodies of the wood-rotting fungus Phlebia chryoscrea. The compounds, named phlebiachrysoic acids A-E are strong inhibitors of leukotriene biosynthesis and are responsible for the red colour reaction when the fruitbodies are touched with aqueous alkali.