ANALYSIS OF ACETYLCYSTEINE BY CAPILLARY ELECTROPHORESIS (CE) .2. DETERMINATION OF SIDE COMPONENTS

Authors
WATZIG H DETTE C AIGNER A WILSCHOWITZ L
Citation
H. Watzig et al., ANALYSIS OF ACETYLCYSTEINE BY CAPILLARY ELECTROPHORESIS (CE) .2. DETERMINATION OF SIDE COMPONENTS, Die Pharmazie, 49(4), 1994, pp. 249-252
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
49
Issue
4
Year of publication
1994
Pages
249 - 252
Database
ISI
SICI code
0031-7144(1994)49:4<249:AOABCE>2.0.ZU;2-4
Abstract
The purity of N-acetyl-L-cysteine was tested by capillary electrophore sis (CE). The efficiency was optimized up to a theoretical plate numbe r N of several hundred thousand. The most important impurities, N,N-di acetylcystine and cystine were detectable in amounts below 0.05%. Thes e and other possible by-products were synthesized and their identity w as confirmed by NMR spectroscopy. All these compounds could be separat ed.