STORAGE AND PHOTOSTABILITY OF CYCLODEXTRI N INCLUSION-COMPOUNDS OF LEMON, ORANGE, HOP, AND CHAMOMILE OIL

The long term stability of lemon oil, orange oil, hop oil, and chamomi le oil as beta- or gamma-cyclodextrin (CD) inclusion compound was exam ined. The storage was performed for up to 2 years. Furthermore, examin ation of the photostability were done. Closed storage of the beta-CD i nclusion compounds of lemon oil, orange, and hop oil allowed an almost total avoidance of instabilities with the three included oils. Storag e in non-closed containers offers no total safety because of the possi ble influence of humidity. The fast deterioration of chamazulene in ch amomile oil is decelerated by gamma-CD. Photochemical changes can be a voided or diminished by inclusion formation. This is proven by the dim inished formation of p-cymene in the lemon oil/beta-CD inclusion compo und, the reduced deterioration of myrcene and the formation of carveol and carvene in the orange oil/beta-CD inclusion compound and the larg e avoidance of the oxidation of linalool in the hop oil/beta-CD inclus ion compound. The increase of photostability of chamomile oil by IJ-CD is low.