We present four unusual colonic complications of acute lymphoblastic l
eukaemia which occurred during the early induction period of chemother
apy. These included a transverse colitis, a haemorrhagic proctitis, a
caeco-colic intussusception and an ileo-colic intussusception complica
ting typhlitis. Although complications are rare, they should be consid
ered in the differential diagnosis of abdominal pain in children under
going chemotherapy.