Ss. Deshmukh et al., MEDIUM OPTIMIZATION FOR THE PRODUCTION OF GLUCOSE-ISOMERASE FROM THERMOPHILIC STREPTOMYCES-THERMONITRIFICANS, World journal of microbiology & biotechnology, 10(3), 1994, pp. 264-267
A thermophilic strain of Streptomyces thermonitrificans produced a hig
h activity of intracellular glucose isomerase (12 U/ml) when grown in
a medium containing 1% (w/v) xylose, supplemented with 2% (w/v) sorbit
ol as the second carbon source, at 50-degrees-C for 16 h. Addition of
Mg2+ enhanced enzyme production but the organism could grow and produc
e the enzyme in the absence of Co2+.