Epidemiological data reveal a decline in the incidence of appendicitis
and appendectomy in the industrialized countries. A peak is found in
adolescents aged 10-19 years; however, the highest rates of perforatio
n are reported for the extremely young and old age groups. The elevate
d rate of appendectomies without histological evidence of acute inflam
mation, especially in young women, and the high perforation ratio in s
mall children and elderly patients reflect poor diagnostic accuracy. A
nalysis of the epidemiological data does not allow for an unequivocal
conclusion regarding the etiopathogenesis of acute appendicitis.