Objective: To provide a concise review of the history technology, theo
ry, limitations and outcomes of pulse oximetry. Data sources and selec
tion: Articles published in major medical journals since 1985 critical
ly appraising pulse oximetry were reviewed, as were numerous historica
l papers. Result: The pulse oximeter is an imperfect device, with nume
rous potential limitations. Conclusion: The pulse oximeter is reasonab
ly accurate under most conditions. However, its reliability diminishes
as the clinical situation deviates from the norm, possibly when accur
acy is most needed.