CASE-REPORT - MULTIPLE INTRACRANIAL METASTASES FROM A PROLACTIN-SECRETING PITUITARY-TUMOR

Only seven cases of metastatic prolactin-secreting pituitary tumour ha ve been reported in world literature. The metastases were intra-crania l in five cases and extra-cranial in two cases. We report a further ca se with multiple intra-cranial metastases in the supra-tentorial compa rtment. Histologically, both primary and metastatic tumours were benig n with strongly positive immuno-histochemical staining for prolactin. Our case exemplifies the inconsistent correlation between the histopat hological appearance and biological behaviour of malignant pituitary t umours.