Plants respond to physical injury, such as that caused by foraging ins
ects, by synthesizing proteins that function in general defense and ti
ssue repair. In tomato plants, one class of wound-responsive genes enc
odes proteinase inhibitor (pin) proteins shown to block insect feeding
. Application of many different factors will induce or inhibit pin gen
e expression. Ethylene is required in the transduction pathway leading
from injury, and ethylene and jasmonates act together to regulate pin
gene expression during the wound response.