SQUAMOUS-CELL CARCINOMA OF THE ESOPHAGUS AND FALCONIS ANEMIA

We report the case of a 36-year-old female with Fanconi's anemia who d eveloped a squamous cell carcinoma of the esophagus which was treated by surgery. In the long term, Fanconi's anemia is associated with a hi gh incidence of acute leukemia, liver tumors or squamous cell carcinom as of various organs. The high chromosome breakage of this disease is assumed to be a predisposing factor for malignant development. This el evated tumor incidence must be appreciated if early diagnosis and appr opriate therapy are to be initiated.