A PRACTICAL SYNTHESIS OF GEOMETRICALLY PURE N-BOC-PROTECTED PRIMARY ALLYLIC AMINES

Authors
VANBENTHEM RATM MICHELS JJ HIEMSTRA H SPECKAMP WN
Citation
Ratm. Vanbenthem et al., A PRACTICAL SYNTHESIS OF GEOMETRICALLY PURE N-BOC-PROTECTED PRIMARY ALLYLIC AMINES, Synlett, (5), 1994, pp. 368-370
Citations number
27
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
5
Year of publication
1994
Pages
368 - 370
Database
ISI
SICI code
0936-5214(1994):5<368:APSOGP>2.0.ZU;2-4
Abstract
N-Boc-Protected primary allylic amines are easily prepared from the co rresponding mesylates or halides by using di-tert-butyl imidodicarbona te (Boc2NH) and K2CO3 or Cs2CO3 in a Gabriel-type substitution, follow ed by selective removal of one Boc group with TFA.