Wa. Grana et al., AN ANALYSIS OF AUTOGRAFT FIXATION AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION IN A RABBIT MODEL, American journal of sports medicine, 22(3), 1994, pp. 344-351
Fixation and incorporation of a tendon implanted within the bone pose
theoretical as well as practical concerns for the surgeon who treats i
nstability problems of the knee. Understanding the physiology involved
in graft-bone incorporation is necessary for the appropriate rehabili
tation of patients who undergo anterior cruciate ligament surgery. The
purpose of the study was to examine the histologic and biomechanical
changes of a semitendinosus autograft reconstruction of the anterior c
ruciate ligament in a rabbit model at the graft-bone tunnel interface
in the femur. The results indicate that by 3 weeks, failure of the bon
e-graft-bone or construction is through the intraarticular portion of
the graft, not as a result of pullout from the bone tunnel. Graft fixa
tion of the bone tunnel occurs by an intertwining of graft and connect
ive tissue and anchoring of connective tissue to bone by collagenous f
ibers and bone formation in the tunnels. The collagenous fibers have t
he appearance of the Sharpey's fibers seen in an indirect tendon inser
tion.