PURPOSE: This study was designed to formulate management guidelines fo
r a variety of rare iatrogenic and accidental injuries to the colon an
d rectum. METHODS: This review collates the available evidence in the
literature. RESULTS: Both investigative and therapeutic maneuvers invo
lving the colon, particularly endoscopy and radiographic contrast stud
ies, are the most common cause of significant injury although the inci
dence is low. Even less common are injuries produced, at open surgery
and minimally invasive surgery, by foreign bodies, enemas, or compress
ed air. The mechanisms and management of these injuries are discussed
in detail. CONCLUSIONS: Evidence exists to support that a nonoperative
approach is safe for the majority of injuries, particularly when the
colon is ''clean'' at the time of injury. Adequate resuscitation, obse
rvation, and repeated reassessment are main stays of a conservative po
licy. Operation is essential for progression of abdominal signs. Patie
nts with established peritonitis at the time of presentation or with a
n unprepared bowel are best served by prompt operation.