SECONDARY METABOLITES BY CHEMICAL-SCREENING .26. 7-0-BETA-D-GALACTOSYL-BREFELDIN-A VIA TRANSGLYCOSYLATION WITH PENICILLIUM BREFELDIANUM

Authors
GRABLEY S THIERICKE R WINK J HENNE P PHILIPPS S WESSELS P ZEECK A
Citation
S. Grabley et al., SECONDARY METABOLITES BY CHEMICAL-SCREENING .26. 7-0-BETA-D-GALACTOSYL-BREFELDIN-A VIA TRANSGLYCOSYLATION WITH PENICILLIUM BREFELDIANUM, Journal of natural products, 57(4), 1994, pp. 541-544
Citations number
12
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
57
Issue
4
Year of publication
1994
Pages
541 - 544
Database
ISI
SICI code
0163-3864(1994)57:4<541:SMBC.7>2.0.ZU;2-D
Abstract
A lactose-containing fermentation medium initiated the formation of 7- O-beta-D-galactosyl-brefeldin A [1] in the brefeldin A-producing organ ism, Penicillium brefeldianum. The detection, isolation, and physicoch emical properties of 1, which has been produced by biological derivati zation via transglycosylation, are described. Compound 1 is the first glycosylated brefeldin A derivative to have been prepared.