MAXAQUIN AND CIPROFLOXACINE TREATMENT OF COMPLICATED AND RECURRENT URINARY INFECTIONS

Clinical efficacy of maxaquin versus ciprofloxacine against complicate d or/and recurrent urinary infections (62 patients primarily with chro nic pyelonephritis with nephrolythiasis) proved higher (92.3 % vs 80.0 %) in equal microbiological activity (73.2 % vs. 73.4 %) of the drugs . Maxaquin was less active in enhancing the culture resistance. Both q uinolones had no negative effects on the studied systems of the body's antiinfectious resistance and promoted partial correction of dysbioti c manifestations on the colon mucosa. Side effects of both drugs occur red with similar frequency and severity, starting earlier in administr ation of maxaquin. The authors offer to manage urinary infections in a dults effectively with maxaguin in a dose 400 mg once a day and ciprof loxacine in a dose 500 mg twice a day by 7-14-da courses.