REFLUX ESOPHAGITIS IN INFANTS AND CHILDREN - A REPORT FROM THE WORKING GROUP ON GASTROESOPHAGEAL REFLUX DISEASE OF THE OCIETY-OF-PEDIATRIC-GASTROENTEROLOGY-AND-NUTRITION
Y. Vandenplas et al., REFLUX ESOPHAGITIS IN INFANTS AND CHILDREN - A REPORT FROM THE WORKING GROUP ON GASTROESOPHAGEAL REFLUX DISEASE OF THE OCIETY-OF-PEDIATRIC-GASTROENTEROLOGY-AND-NUTRITION, Journal of pediatric gastroenterology and nutrition, 18(4), 1994, pp. 413-422
In this article, the Working Group on Gastro-Oesophageal Reflux of the
European Society of Paediatric Gastroenterology and Nutrition present
s and discusses a definition of reflux esophagitis and recommends a di
agnostic approach and therapeutic management for this condition. Histo
logic criteria for reflux esophagitis, modified and adapted to the par
ticular needs of infants and children, are suggested. Upper gastrointe
stinal endoscopy is recommended as the technique of choice in infants
and children presenting with symptoms suggestive of reflux esophagitis
. Prokinetics, although still a relatively new drug family, have alrea
dy established a definitive place in the treatment of gastroesophageal
reflux disease in infants and children and could also be used in the
treatment of nonulcerative esophagitis, as suggested in the literature
. If the esophagitis is more severe (ulcerative), treatment should ini
tially consist of H-2 blockers and then be continued with prokinetics.
New drugs, such as omeprazole, are suggested in cases refractory to H
-2 blockers. Surgery is indicated in life-threatening conditions or if
the esophagitis is resistant to adequate medical management.