Ga. Fava et al., NEUROCIRCULATORY ASTHENIA - A REASSESSMENT USING MODERN PSYCHOSOMATICCRITERIA, Acta psychiatrica Scandinavica, 89(5), 1994, pp. 314-319
The purpose of this study was to assess the prevalence of mental illne
ss and to evaluate the quality of life of patients with neurocirculato
ry asthenia. A consecutive series of 80 patients who satisfied the dia
gnostic criteria developed by Kannel et al. for neurocirculatory asthe
nia was included in this study. Patients underwent a psychiatric diagn
ostic research interview and extensive psychometric evaluation, with b
oth observer and self-rated scales for depression, anxiety, phobic sym
ptoms, quality of life and abnormal illness behavior. In 47 patients (
59%), a psychiatric diagnosis (mainly an anxiety disorder) antedated t
he onset of neurocirculatory asthenia, which was thus defined as secon
dary, also because cardiorespiratory symptoms were part of the mental
symptoms. In the remaining 33 patients (41%) neurocirculatory asthenia
was the primary disorder. Patients with secondary neurocirculatory as
thenia reported significantly higher levels of anxiety, depression, so
cial phobia, abnormal illness behavior and an impaired quality of life
compared with patients with primary neurocirculatory asthenia. This l
atter did not significantly differ in these variables (except for depr
ession) from healthy control subjects matched for sociodemographic var
iables. At a 1-year follow-up, patients with primary neurocirculatory
asthenia had a much better prognosis than those with secondary neuroci
rculatory asthenia. The results indicate the feasibility of the primar
y/secondary distinction based on the time of onset of mental and cardi
orespiratory symptoms in neurocirculatory asthenia. Since only about o
ne quarter of the patients were found to suffer from decreased energy
and fatigue according to specified criteria, the terms neurocirculator
y asthenia and effort syndrome should probably be discarded.