TOXIC EPIDERMAL NECROLYSIS WITH TRACHEOBRONCHIAL AND PULMONARY COMPLICATIONS

A 55-year-old man developed multiple erythematous skin lesions after s urgery for acoustic neurinoma. Necrosis and detachment of the epidermi s developed and a diagnosis of toxic epidermal necrolysis (TEN) was ma de. Progressive dyspnea was evident two days after the onset of the sk in lesions. Chest X-ray revealed diffuse interstitial shadows in both lung fields. On bronchoscopic examination, erosion, vesicle formation, necrosis and desquamation of the epidermis were seen in the tracheobr onchial mucosa. Therapy, including prednisolone, improved the skin les ions as well as the chest X-ray and bronchoscopic findings. Tracheobro nchial and pulmonary lesions were followed before, during and after tr eatment of TEN.