The design of spectroscopic measurements of the atmosphere with the li
mb-scanning technique for the retrieval of constituent altitude profil
es requires choosing instrumental, observational, and retrieval parame
ters. An approach to this problem is discussed, and the mathematical t
ools that make it possible to study the trade-off between the two conf
licting requirements of optimum vertical resolution and small error of
the profile are derived. As a first illustrative application, impleme
ntation of the mathematical tools in the design of measurements to be
carried out from a satellite platform is shown; a set of parameters th
at provide a satisfactory compromise between the vertical resolution a
nd the uncertainties of the retrieved profile has been identified. The
mathematical model discussed can simulate the results obtained with r
etrieval techniques that are based on the global inversion of the kern
el that relates the observations and the unknown, profile. As a second
application, a comparison between the a priori estimate of the uncert
ainties provided by the mathematical tools and the results of the glob
al analysis of data collected with a balloon-borne experiment is shown
.