Eighty patients suffering from tension-type headache for an average of
21 years were asked to report on all drugs they had ever taken (type,
dosage, duration of intake, efficacy) or were taking currently. The p
atients had consumed on average 6.3 different drugs. The cumulative do
ses of derivatives of para-aminophenol, pyrazolone, and salicylic acid
in some cases reached a maximum of several kilograms. Most drugs were
classified by the patients as ''moderately.effective''. The rating ''
very effective'' was assigned primarily to barbiturates; however, barb
iturates are no longer used as components of compound analgesic drugs
in Austria. At the time of investigation, patients consumed 2.5 (mean)
different drugs, primarily as compound preparations. Seventeen patien
ts (21%) showed signs of possible analgesics- or ergotamine-induced he
adache and were therefore advised to undergo withdrawal therapy. Our r
esults show that patients with tension-type headache are at considerab
le risk of becoming drug-dependent and of acquiring analgesics-induced
headache.