WITH THE INCREASING NUMBER OF DIABETICS in an aging population and con
troversial research reports on the relationship of diabetes to periodo
ntitis, clarification of diabetes as a risk factor for periodontitis w
ould be helpful. This review notes variations in type, metabolic contr
ol, and duration of diabetes and highlights the results of studies tha
t have considered these variations. Diabetics who maintained reasonabl
y good metabolic control had not lost more teeth or experienced more p
eriodontal attachment loss than non-diabetics, although they had more
periodontal pockets. Poorly-controlled diabetics with extensive calcul
us on their teeth had more periodontitis and tooth loss than well-cont
rolled diabetics or non-diabetics. Long-duration diabetics were also a
t greater risk for periodontitis. Mechanisms by which diabetes may con
tribute to periodontitis include vascular changes, neutrophil dysfunct
ion, altered collagen synthesis, and genetic predisposition. Minimizin
g plaque and calculus in the oral cavity through careful self-care and
regular professional care is important to reduce the risk of periodon
titis in diabetics.