SPECTROSCOPIC CHARACTERIZATION AND IN-VITRO AND IN-VIVO SCREENING OF DIFLUORO-BORON COMPLEXES OF NO AND NS DONOR LIGANDS

Stereochemical and biochemical aspects of some difluoroboron complexes of the types BF2(NS) and BF2(NO) with ligands having (NS) and (NO) do nor systems have been described. Based on IR, H-1 NMR, C-13 NMR, F-19 NMR, and B-11 NMR spectral studies, a tetracoordinated state of boron has been established. In order to assess their growth inhibiting poten cy the ligands and their fluoroboron complexes have been tested in vit ro against a number of pathogenic fungi and bacteria at different conc entrations and were found to possess remarkable fungicidal and bacteri cidal properties. The testicular morphology, testicular sperm density, sperm motility, density of cauda epididymal spermatozoa, and fertilit y in mating trails and biochemical parameters of reproductive organs w ith 2-acetylthiophene thiosemicarbazone, 2-acetylnaphthalene semicarba zone, and their fluoro complexes in vivo have also been examined and d iscussed.