THE EFFECT OF PREBRUSHING MOUTHRINSE SOLUTIONS ON THE DESORPTION OF ALBUMIN FROM APATITE

This study evaluated the desorption of radiolabelled albumin from synt hetic hydroxypatite by 4 commercial prebrushing solutions: Lysoplac (c ontaining chlorhexidine), Plax (sodium benzoate), Acti-Brush (triclosa n), and Sanogyl (sodium fluoride). In 3 min, Lysoplac and Plax were fo und to desorb about 90% of albumin while Acti-Brush and Sanogyl failed to desorb hardly any albumin in 15 min. The desorbing effectiveness o f the test solutions was not due to their pH, because when buffer solu tion was being tested in different ionic strengths at pH range 6-8, it appeared to desorb less than 3% of adsorbed albumin, irrespective of the pH used. The results obtained cannot, however, be directly applied to the clinical situation where much more complex interactions occur than what were tested under the present in vitro conditions.