I. Tsunoda et al., IDIOPATHIC AA AMYLOIDOSIS MANIFESTED BY AUTONOMIC NEUROPATHY, VESTIBULOCOCHLEOPATHY, AND LATTICE CORNEAL-DYSTROPHY, Journal of Neurology, Neurosurgery and Psychiatry, 57(5), 1994, pp. 635-637
A 69-year-old Japanese woman with non-familial amyloidosis had polyneu
ropathy and profound autonomic neuropathy, and kappa chain monoclonal
gammopathy. Immunohistopathological examination showed protein AA and
protein AP in the amyloid deposits. She showed involvement of the vest
ibulocochlear nerve and lattice dystrophy of the cornea. Vestibulococh
leopathy and corneal lattice dystrophy have been reported in familial
amyloid polyneuropathy type IV, Finnish type, but never in non-familia
l amyloidosis.