F. Moonens et al., USEFULNESS OF GRAM STAINING OF BLOOD COLLECTED FROM TOTAL PARENTERAL-NUTRITION CATHETER FOR RAPID DIAGNOSIS OF CATHETER-RELATED SEPSIS, Journal of clinical microbiology, 32(6), 1994, pp. 1578-1579
The accuracy of Gram staining of blood drawn from catheters used to ad
minister total parenteral nutrition was compared,vith paired quantitat
ive blood cultures for the diagnosis of catheter-related sepsis. Gram
staining was positive in 11 of 18 episodes of catheter-related sepsis
documented by quantitative culture (sensitivity, 61%) but in none of t
he 5 episodes of fever unrelated to catheter infection. Thus, this pro
cedure enabled the rapid presumptive diagnosis and guidance of antimic
robial therapy for total parenteral nutrition catheter sepsis, with a
positive predictive value of 100% and a negative predictive value of 4
2%.