EFFECT OF CENTRIFUGING SHELL VIALS AT 3,500XG ON DETECTION OF VIRUSESIN CLINICAL SPECIMENS

An increase in shell vial centrifugation force to 3,500 x g and a conc omitant reduction in spin time to 15 min did not decrease the sensitiv ity of detecting viruses in clinical specimens compared with the accep ted practice of using 700 x g for 40 min. No damage to the cell monola yer (ML) at the higher g force was observed. Toxicity to the ML is dec reased with the shorter spin, probably because of reduced time of cont act between the specimen and the ML.