Aims: The authors report their experience on the treatment of 28 cases
of middle ear (3) and external auditory meatus (EAM) cancers (25) wit
h surgery and/or radiation therapy. According to histologic type, ther
e were 23 squamous cell carcinomas, 4 basal cell carcinomas and 1 aden
ocystic carcinoma. Methods: Surgery alone was performed in 2 cases, su
rgery combined with radiotherapy in 11 cases, and radiotherapy alone i
n 15 cases. Postoperative radiation therapy dose ranged between 4500 a
nd 5500 cGy; the definitive dose was 6000-7000 cGy. The median follow-
up was 61 months. Results: Complete respons rate 6 weeks after the end
of the treatment, evaluated by CT scan, was 85.7% (24/28). Definitive
local control was obtained in 20/28 cases for the primary site and in
26/28 cases for the neck. Nine of the 10 recurrences were retreated w
ith low-dose radiotherapy combined with surgery, chemotherapy or hyper
thermia. A new local control was obtained in 2 cases. Four patients we
re lost during the follw-up at 13, 14,17 and 23 months after the end o
f the treatment. The survival rate was 54% (13/24); disease-free survi
val was 50% (11/22). Conclusions: Despite a not very aggressive treatm
ent, our results are quite good.