REACTION OF ENAMINONITRILES WITH ISOCYANATES - SYNTHESIS OF NEW 2-OXOPYRIMIDINES AND 6-OXOPYRIMIDINES

Authors
COCCO MT CONGIU C MACCIONI A ONNIS V
Citation
Mt. Cocco et al., REACTION OF ENAMINONITRILES WITH ISOCYANATES - SYNTHESIS OF NEW 2-OXOPYRIMIDINES AND 6-OXOPYRIMIDINES, Journal of heterocyclic chemistry, 31(2), 1994, pp. 329-334
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
2
Year of publication
1994
Pages
329 - 334
Database
ISI
SICI code
0022-152X(1994)31:2<329:ROEWI->2.0.ZU;2-3
Abstract
The reaction of enaminonitriles 1 with aryl or benzyl isocyanates affo rded C-3-5 or N-adducts 6-8 or a mixture of both depending on the subs titution pattern of the considered enaminonitrile. The one-step synthe sis of 6-oxopyrimidines 9-11 and 2-oxopyrimidines 12-14 by cyclization of compounds 3-5 and 6-8 respectively is also described.