SYNTHESIS OF DIHYDRO-4-OXOPYRROLO[1,2-B]PYRIDAZINE-3-CARBOXYLIC ACIDSAND DIHYDRO-4-OXOIMIDAZO[1,5-B]PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS

Citation
Jm. Ruxer et al., SYNTHESIS OF DIHYDRO-4-OXOPYRROLO[1,2-B]PYRIDAZINE-3-CARBOXYLIC ACIDSAND DIHYDRO-4-OXOIMIDAZO[1,5-B]PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS, Journal of heterocyclic chemistry, 31(2), 1994, pp. 409-417
Citations number
33
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
0022152X
Volume
31
Issue
2
Year of publication
1994
Pages
409 - 417
Database
ISI
SICI code
0022-152X(1994)31:2<409:SODA>2.0.ZU;2-F
Abstract
To check the antibacterial potential of two families of aza analogues of the quinolones, dihydro-4-oxopyrrolo[1,2-b]pyridazine-3-carboxylic acids and dihydro-4-oxoimidazo[1,5-b]pyridazine-3-carboxylic acids, we have prepared a few derivatives in theses families using N-aminopyrro le and N-aminoimidazole derivatives as starting building blocks and th e classical pathways of the quinolone series. The compounds showed no interesting antibacterial activity.