SYNTHESIS OF DIHYDRO-4-OXOPYRROLO[1,2-B]PYRIDAZINE-3-CARBOXYLIC ACIDSAND DIHYDRO-4-OXOIMIDAZO[1,5-B]PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS
Jm. Ruxer et al., SYNTHESIS OF DIHYDRO-4-OXOPYRROLO[1,2-B]PYRIDAZINE-3-CARBOXYLIC ACIDSAND DIHYDRO-4-OXOIMIDAZO[1,5-B]PYRIDAZINE-3-CARBOXYLIC ACIDS AS POTENTIAL ANTIBACTERIAL AGENTS, Journal of heterocyclic chemistry, 31(2), 1994, pp. 409-417
To check the antibacterial potential of two families of aza analogues
of the quinolones, dihydro-4-oxopyrrolo[1,2-b]pyridazine-3-carboxylic
acids and dihydro-4-oxoimidazo[1,5-b]pyridazine-3-carboxylic acids, we
have prepared a few derivatives in theses families using N-aminopyrro
le and N-aminoimidazole derivatives as starting building blocks and th
e classical pathways of the quinolone series. The compounds showed no
interesting antibacterial activity.