O. Reish et al., HEMOPHILIA AND IN A NEONATE - UNUSUAL EARLY SPONTANEOUS GASTROINTESTINAL-BLEEDING, American journal of perinatology, 11(3), 1994, pp. 192-193
A full-term male, healthy newborn infant suddenly developed melena and
rectal fresh blood oozing at age of 4 days. He is the second patient
described in the literature presenting a spontaneous gastrointestinal
bleeding in the neonatal period as the first clinical manifestation of
hemophilia B. The early appearance and severity of the hemorrhage, it
s short duration, and good response to Factor IX (inefficiency of vita
min K) was the characteristics of the affected neonate. Whenever a new
born presents early spontaneous gastrointestinal bleeding, hemophilia
B should be considered a possible etiology and blood coagulation studi
es should be performed accordingly.