GENETIC-ANALYSIS OF A MENINGOCOCCAL POPULATION-BASED ON POLYMORPHISM OF THE PILA-PILB LOCUS - A MOLECULAR APPROACH FOR MENINGOCOCCAL EPIDEMIOLOGY

Authors
GUIBOURDENCHE M GIORGINI D GUEYE A LARRIBE M RIOU JY TAHA MK
Citation
M. Guibourdenche et al., GENETIC-ANALYSIS OF A MENINGOCOCCAL POPULATION-BASED ON POLYMORPHISM OF THE PILA-PILB LOCUS - A MOLECULAR APPROACH FOR MENINGOCOCCAL EPIDEMIOLOGY, Journal of clinical microbiology, 35(3), 1997, pp. 745-750
Citations number
20
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
35
Issue
3
Year of publication
1997
Pages
745 - 750
Database
ISI
SICI code
0095-1137(1997)35:3<745:GOAMPO>2.0.ZU;2-V
Abstract
The genetic relationships between 88 meningococcal strains were analyz ed by using the polymorphism of the pilA gene and the multilocus enzym e electrophoresis. While a good agreement was observed, correlation wi th antigenic formula (serogroup, serotype, and serosubtype) was incomp lete. The inadequacy of serological classification alone in outbreak s urveillance may be overcome by DNA-based approaches.