DRUG CARRIERS FOR TRANSDERMAL PREPARATIONS OF FLURBIPROFEN

Authors
SINGH UV PANDEY S UDUPA N
Citation
Uv. Singh et al., DRUG CARRIERS FOR TRANSDERMAL PREPARATIONS OF FLURBIPROFEN, Drug development and industrial pharmacy, 20(10), 1994, pp. 1811-1820
Citations number
10
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Drug development and industrial pharmacy → ACNP
ISSN journal
03639045
Volume
20
Issue
10
Year of publication
1994
Pages
1811 - 1820
Database
ISI
SICI code
0363-9045(1994)20:10<1811:DCFTPO>2.0.ZU;2-9
Abstract
Flurbiprofen was incorporated in different carriers like sodium algina te gel, calcium alginate microspheres, gelatin nanoparticles and compl ex with betacyclodextrin and incorporated in polyethylene glycol bases . Pharmacodynamic and bioavailability studies were carried out in male rats. It was found that drug incorporated in sodium alginate gel and drug complexed with betacyclodextrin Were found to be suitable for des igning transdermal preparations since they resulted in better therapeu tic efficacy.