The effects of an antisiphon device (ASD) on shunt flow and intracrani
al pressure (ICP) in 16 children with hypertensive hydrocephalus were
examined using quantitative radionuclide shuntography (Tc-99m) with th
e children in supine and sitting positions. The average age of these p
atients was 9.5 years. Results were compared with those recorded in 36
patients with adult normal-pressure hydrocephalus (NPH). The closing
pressure levels of shunt valve used were low in 8 cases, medium in 7 a
nd high in 1. Half the children (8) had shunt systems with, and the ot
her 8 without, ASD. In the children who had the shunt system without A
SD, sitting shunt flow was significantly greater than supine shunt flo
w, which indicated overdrainage. Conversely, in children who had the s
hunt system with ASD, supine shunt flow was greater than sitting shunt
flow. Because ASD prevented overdrainage, ICP was higher with the shu
nt system with ASD than with the shunt system without ASD. Without ASD
, sitting shunt flow of children was lower than that of adult patients
with NPH because of the lower hydrostatic pressure, which correlated
with their height. Conversely, in the presence of a shunt system with
ASD, sitting shunt flow of children was greater than that of adults, b
ecause of the higher ICP and lower hydrostatic pressure. The effect of
ASD was smaller in children than in adults, because positive pressure
over the ASD was greater (hypertension vs normal pressure) and negati
ve pressure under the ASD was less (short vs tall) in children than in
adults. Thus, in children the ASD was effective in preventing overdra
inage. An overfunction of the ASD, which has sometimes been observed i
n adult patients with NPH, was not encountered. The relationships amon
g the function of the ASD and ICP, height and position of the ASD are
discussed.