Ac. Hinz et al., THE UTILITY OF THE INTRACAROTID AMYTAL PROCEDURE IN DETERMINING HEMISPHERIC SPEECH LATERALIZATION IN PEDIATRIC EPILEPSY PATIENTS UNDERGOINGSURGERY, Child's nervous system, 10(4), 1994, pp. 239-243
The usefulness of the intracarotid Amytal (amobarbital) procedure (als
o called the Wada procedure) in identifying hemispheric language domin
ance in pediatric patients has not been independently confirmed with i
ntraoperative language mapping techniques. Currently, data are extrapo
lated from adult studies. To better establish the usefulness of the in
tracarotid Amytal procedure in identifying hemispheric language domina
nce in pediatric patients, we reviewed the records of 77 consecutive p
ediatric patients who underwent sodium amobarbital testing. Among thes
e 77 subjects, 34 underwent intraoperative language mapping, the resul
ts of which all completely confirmed the Amytal results. It was also s
hown that among these pediatric epileptic patients who underwent Amyta
l testing, there existed not only a strong correlation between left-ha
ndedness and atypical speech lateralization (right, bilateral hemisphe
re), but also between right-sided hemiparesis (i.e., early left-hemisp
here injury) and atypical speech.