SOME DIFFICULT SEQUENCES MADE EASY - A STUDY OF INTERCHAIN ASSOCIATION IN SOLID-PHASE PEPTIDE-SYNTHESIS

Authors
HYDE C JOHNSON T OWEN D QUIBELL M SHEPPARD RC
Citation
C. Hyde et al., SOME DIFFICULT SEQUENCES MADE EASY - A STUDY OF INTERCHAIN ASSOCIATION IN SOLID-PHASE PEPTIDE-SYNTHESIS, International journal of peptide & protein research, 43(5), 1994, pp. 431-440
Citations number
21
Categorie Soggetti
Biology
Journal title
International journal of peptide & protein research → ACNP
ISSN journal
03678377
Volume
43
Issue
5
Year of publication
1994
Pages
431 - 440
Database
ISI
SICI code
0367-8377(1994)43:5<431:SDSME->2.0.ZU;2-F
Abstract
Case studies of the solid-phase synthesis of some 'difficult sequences ' using continuous-flow Fmoc-polyamide techniques are presented. Solve nt change and peptide side chain and backbone modification procedures recently found to reduce association effects are applied, and the resu lts compared to syntheses under standard conditions. (C) Munksgaard 19 94.