ANALYSIS OF GENOTYPE AND PHENOTYPE ON THE SAME INTERPHASE OR MITOTIC CELL - A MANUAL OF MAC (MORPHOLOGY ANTIBODY CHROMOSOMES) METHODOLOGY

Citation
S. Knuutila et al., ANALYSIS OF GENOTYPE AND PHENOTYPE ON THE SAME INTERPHASE OR MITOTIC CELL - A MANUAL OF MAC (MORPHOLOGY ANTIBODY CHROMOSOMES) METHODOLOGY, Cancer genetics and cytogenetics, 72(1), 1994, pp. 1-15
Citations number
100
Categorie Soggetti
Oncology,"Genetics & Heredity
ISSN journal
01654608
Volume
72
Issue
1
Year of publication
1994
Pages
1 - 15
Database
ISI
SICI code
0165-4608(1994)72:1<1:AOGAPO>2.0.ZU;2-C
Abstract
The purpose of this paper is to serve as a MAC (Morphology Antibody Ch romosome) manual describing combined methodologies that allow simultan eous and/or sequential analysis of cell morphology, immunophenotype, a nd banded chromosomes and/or in situ hybridization signals. The MAC te chniques used at the Department of Medical Genetics of the University of Helsinki, Finland, are described and modifications or related techn iques reported by other authors are discussed. A list of references co ncerning applications is also given.