STUDIES ON STANDARDIZATION OF FOLIUM-STROBILANTHIS, RADIX-STROBILANTHIS AND THEIR PREPARATIONS

Authors
LI L DONG TY LI XL QIAO CZ
Citation
L. Li et al., STUDIES ON STANDARDIZATION OF FOLIUM-STROBILANTHIS, RADIX-STROBILANTHIS AND THEIR PREPARATIONS, BMC. Biomedical chromatography, 8(3), 1994, pp. 145-147
Citations number
7
Categorie Soggetti
Chemistry Analytical","Pharmacology & Pharmacy",Biology
Journal title
BMC. Biomedical chromatography → ACNP
ISSN journal
02693879
Volume
8
Issue
3
Year of publication
1994
Pages
145 - 147
Database
ISI
SICI code
0269-3879(1994)8:3<145:SOSOFR>2.0.ZU;2-G
Abstract
Determination of 4(3H)-quinazolinone, a newly found antiviral and immu nopatentiating constituent was proposed as a method of evaluating the quality of two antiviral Chinese herbal drugs Daqingye (Folium Strobil anthis) and Banlangen(Radix Strobilanthis) and their preparations ('An tipyretic and common cold granules', 'Banlangen granules'). An HPLC me thod for determining the content of 4(3H)-quinazolinone was establishe d with satisfactory results. The method showed good linearity (r=0.999 8, n=5) in the range of 0. 25-50 mug/mL of 4(3H)-quinazolinone, the av erage recovery was above 99% with RSD < 0.78% (n = 3).