AMINO-ACIDS, PEPTIDES AND HETEROCYCLIC CH EMISTRY

In this report the importance of heterocycles in amino acid and peptid e chemistry is pointed out. Neuroexcitatory amino acids, kainic acid, quisqualic acid , of which new syntheses are given, are representative examples of the role of the heterocycle in the recognition of recepto r sites. It is also shown that a heterocyclic structure can replace ad vantageously a peptide turn. The synthesis of a functionnalized diazep inone, a gamma-turn mimetic, is described