INTRODUCTION OF A CAGE SYSTEM IN SOME NON STEROIDAL ANTALGICS BY ALKYLATION UNDER PHASE-TRANSFER CATALYSIS CONDITIONS AND BY A NONCATALYTICPROCEDURE WITH A DERIVATIVE OF ADAMANTANE

Authors
HEDAYATULLAH M NACHAWATI I MAROUFI E
Citation
M. Hedayatullah et al., INTRODUCTION OF A CAGE SYSTEM IN SOME NON STEROIDAL ANTALGICS BY ALKYLATION UNDER PHASE-TRANSFER CATALYSIS CONDITIONS AND BY A NONCATALYTICPROCEDURE WITH A DERIVATIVE OF ADAMANTANE, Bulletin des Societes chimiques belges, 103(1), 1994, pp. 27-30
Citations number
8
Categorie Soggetti
Chemistry
Journal title
Bulletin des Societes chimiques belges → ACNP
ISSN journal
00379646
Volume
103
Issue
1
Year of publication
1994
Pages
27 - 30
Database
ISI
SICI code
0037-9646(1994)103:1<27:IOACSI>2.0.ZU;2-O
Abstract
The alkylation of a series of non-steroidal antalgics by a derivative of adamantane, under phase transfer conditions and by a non-catalytic procedure was achieved in high yield. In most cases, the new cage stru ctures exhibited more analgesic activity than the corresponding non-al kylated compounds.