Sa. Schafer et al., MECHANISMS OF BILIARY STONE FRAGMENTATION USING THE HO-YAG LASER, IEEE transactions on biomedical engineering, 41(3), 1994, pp. 276-283
We have investigated the fragmentation of gallstones using the pulsed
Ho:YAG laser, comparing it to lithotripsy using the visible pulsed-dye
laser. We find that the physical mechanisms of stone fragmentation ap
pear to be quite different in the two cases. Using high-speed photogra
phy, measurement of acoustic transients, time-resolved optical emissio
n spectroscopy, and direct microscopic observation, we have analyzed t
he interaction of the Ho:YAG laser with both water and gallstones. We
propose a new model in which fragmentation begins with absorption of t
he laser light by the stone surface. This is followed by melting and e
jection of stone material, which is then swept away by the vapor bubbl
e formed by the absorption of the Ho:YAG laser light by water. This mo
del is in excellent agreement with our experimental observations, and
differs substantially from the model developed by Teng et al. for lase
r lithotripsy using the visible pulsed-dye laser.