While carotid endarterectomy (CEA) can often be accomplished with a ve
ry low stroke risk, certain scenarios-prior ipsilateral stroke, contra
lateral carotid occlusion, or acute cerebral ischemia-have been associ
ated with neurologic morbidity and mortality rates exceeding 10%. The
routine use of temporary intraluminal carotid shunts has been thought
to he obligatory in such patients, notwithstanding the fact that these
devices are obtrusive and may be associated with an increased risk of
perioperative stroke. Among 175 patients undergoing CEA, 68 could be
classified as ''high-risk'' (contralateral carotid occlusion, n = 24;
prior ipsilateral stroke, n = 28; acute cerebral ischemia, n = 16). CE
A was performed under regional or local anesthetic block in all 68 pat
ients. Sixty-six patients (97%), including 22 of 24 (92%) with contral
ateral carotid occlusion, underwent CEA (carotid occlusion times avera
ging 22 minutes [range: 12 to 42 minutes]) without insertion of a caro
tid shunt. Two patients (2.9%) with contralateral carotid occlusion lo
st consciousness ? and 10 minutes after carotid clamping, but regained
neurologic normalcy after shunt insertion. A single patient (1.5%) ex
perienced a fatal stroke due to heparin-induced ''white clot'' syndrom
e. Rates of shunt insertion and of perioperative stroke did not differ
from those in 107 ''low-risk'' CEA patients. Cerebral collateral circ
ulation is well developed even in compromised CEA patients. The necess
ity for temporary carotid shunts may be reduced by the use of ''awake'
' anesthesia in such cases. Carotid shunting may be no more necessary,
and operative outcome no less favorable; in ''high-risk'' than in unco
mplicated CEA patients.