GASTRIC RELAXATION IN RESPONSE TO CHEMICAL-STIMULATION OF THE AREA POSTREMA IN THE RABBIT

Authors
BONGIANNI F MUTOLO D SRINIVASAN M STADERINI G BACCARI MC CALAMAI F PANTALEO T
Citation
F. Bongianni et al., GASTRIC RELAXATION IN RESPONSE TO CHEMICAL-STIMULATION OF THE AREA POSTREMA IN THE RABBIT, Brain research, 646(2), 1994, pp. 307-311
Citations number
23
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
646
Issue
2
Year of publication
1994
Pages
307 - 311
Database
ISI
SICI code
0006-8993(1994)646:2<307:GRIRTC>2.0.ZU;2-1
Abstract
Microinjections of DL-homocysteic acid into the area postrema (AP) of anesthetized rabbits provoked gastric relaxations associated with smal l changes in blood pressure and marked excitatory effects on respirati on. Both gastric and cardiovascular effects failed to occur after bila teral vagotomy. Comparable gastric relaxations were induced before and after treatment with atropine or atropine and guanethidine. The A9 ap pears to play a role in gastric motility via vagus nerves and nonadren ergic noncholinergic intramural inhibitory neurons.